Afectats amb Síndrome de Down pateixen més malalties autoimmunitàries

La proteïna AIRE controla la resposta dels limfòcits perquè ataquin organismes exteriors i evitin atacs en cèl·lules del propi cos

CARLA radio / anunci.info Barcelona (ACN).- Un equip d’investigadors del grup d’Immunologia del Vall d’Hebron Institut de Recerca (VHIR) ha descobert que els individus amb Síndrome de Down tenen menys expressada la proteïna reguladora de l’autoimmunitat, anomenada AIRE, que controla la resposta dels limfòcits perquè ataquin organismes exteriors i evitin atacs en cèl·lules del propi cos. Per descobrir-ho, els investigadors van analitzar el timus, l’òrgan limfàtic, de pacients recent operats de cardiopaties congènites. Així, han descobert que els individus amb Síndrome de Down tenen més predisposició a patir malalties autoimmunitàries com ara la diabetis, la celiaquia o l’hipotiroïdisme.
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