Investigadors de la UB identifiquen una proteïna clau en el desenvolupament del càncer de pàncrees

L’estudi, que ha estat publicat a la revista ‘Gastroenterology’, obre noves dianes terapèutiques

CARLA radio / anunci see this Barcelona (ACN).- Investigadors de la Universitat de Barcelona (UB) han detectat una relació fins ara desconeguda entre una proteïna anomenada HNRNPA2B1 i el desenvolupament del càncer de pàncrees. La investigació, que s’ha publicat aquest dilluns a la revista ‘Gastroenterology’, ha revelat que en línies cel·lulars humanes cancerígenes (in vitro i in vivo) aquesta proteïna és essencial perquè funcioni la proteïna KRAS oncogènica, vinculada amb l’inici i la progressió tumoral. Segons els professionals, la interacció entre la proteïna HNRNPA2B1 i la proteïna codificada pel gen KRAS és una diana terapèutica potencial per al tractament del càncer de pàncrees, un dels càncers amb pitjor pronòstic.

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