Fàrmacs antidiabètics podien reduir la resistència a la insulina

Alguns fàrmacs antidiabètics podien reduir la resistència a la insulina i facilitar que els teixits siguin més sensibles a l’hormona

Un estudi de la UB i l’IDIBAPS obre la porta a nous mètodes curatius de la diabetis 2

anunci.info Barcelona (ACN).- En la diabetis de tipus 2, els teixits no responen al senyal de la insulina, perquè en són resistents, i els malalts acaben patint hiperglucèmia, ja que les cèl·lules no poden captar la glucosa. Un estudi d ela UB i l’IDIBAPS, ha comprovat que les tiazolidinediones (TZD), antidiabètics orals, redueixen aquesta resistència a la insulina i faciliten que els teixits siguin més sensibles a l’acció d’aquesta hormona. Els investigadors han descobert que les TZD inhibien un transductor de senyals bioquímics que al seu torn, inhibeix la senyalització d’insulina. L’estudi també aporta evidències que les TZD poden actuar al pàncrees, i obre noves vies d’estudi sobre el control del metabolisme de la glucosa.

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