La investigació ha estat liderada per Manel Esteller i ha analitzat el genoma de 36 parells de germanes
Diferència epigenètica en bessones explica el diferent risc de patir càncer de mama
anunci.info Barcelona (ACN).- Un estudi de l’Institut d’Investigació Biomèdica de Bellvitge (IDIBELL) ha conclòs que una diferència epigenètica és la causa de que bessones idèntiques tinguin diferent risc de patir càncer de mama i una el desenvolupi i l’altre no. Els bessons monozigòtics tenen el mateix genoma però poden presentar malalties diferents en temps diferents. Això s’explicat perquè els senyals químics que s’afegeixen a l’ADN, que és idèntic en les dues bessones, per ‘apagar’ o ‘engegar’ els gens poden ser diferents, per tant, tenen diferents marques epigenètiques. L’estudi, liderat per l’investigador Manel Esteller, ha identificat que només es dóna aquest canvi epigenètic en la bessona que desenvoluparà càncer de mama.
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